Friday, February 17, 2017

More about T-cells and B-cells that protect your body from invaders

Our immune system is one of nature’s most fascinating inventions of our body.  It protects us against billions of bacteria, viruses, parasites and fungi with ease.  Most of us never reflect upon the fact that while we hang out with our friends, go shopping, or go to school, our immune system is constantly on the alert, attacking whatever invaders coming through our skins, mouth, ears, eyes, and also attacking those critters that are multiplying inside our body.

A little info about how they are formed.  There are cells called White blood cells in every human body called lymphocytes, these White blood cells originate in the bone marrow but migrate to parts of the lymphatic system such as the lymph nodes, spleen and thymus.    The lymphatic system also involves a special transportation system – lymph vessels – mainly for transportation and storage of lymphocyte cells within the body.  The lymphatic system feeds cells into the body and filters out dead cells and invading organism such as bacteria.  There are two main types of lymphatic cells, T-cell and B-cells.  As informed earlier, T-cells come in two different types, helper cells and killer cells.  They are called T-cells after the thymus, which is an organ situated under the breastbone.  T-cell produced in the bone marrow and later move to the thymus where they mature.  B-cells are continuously produced in the bone marrow from where they migrate to secondary lymphoid tissues where some develop into mature B cells.


Apart from the T-cells and B-cells and their subset cells.  There is a cell called plasma cell which are derived from B-cells.  The role of the plasma cells is in producing a specific protein, called an antibody that responds to antigen.  Antibodies are released from the plasma cell so that they can seek out invaders and help destroy them.  Plasma cells produces antibodies that too at an amazing rate and that release tens of thousands of antibodies per seconds.  Antibodies trap invading viruses or bacteria in large clumps.  This makes it easy for the macrophages to eat them.  Antibody coated viruses are called “neutralized”, they are so called because they cannot infect your cells, as even after you have fought off your infections, some antibodies stay in your blood.